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(1S,4R)-N-Desmethyl Sertraline Hydrochloride

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Catalog No. T9395Cas No. 675126-07-5

(1S,4R)-N-DesmethylSertralineHydrochloride is a Serotonin transporter and Norepinephrine transporter inhibitor with IC50 of 19 nM and 35 nM, respectively.

(1S,4R)-N-Desmethyl Sertraline Hydrochloride

(1S,4R)-N-Desmethyl Sertraline Hydrochloride

🥰Excellent
Purity: 99.71%
Catalog No. T9395Cas No. 675126-07-5
(1S,4R)-N-DesmethylSertralineHydrochloride is a Serotonin transporter and Norepinephrine transporter inhibitor with IC50 of 19 nM and 35 nM, respectively.
Pack SizePriceAvailabilityQuantity
1 mg$118In Stock
5 mg$280In Stock
10 mg$410In Stock
25 mg$642In Stock
50 mg$870In Stock
100 mg$1,170In Stock
200 mg$1,570In Stock
1 mL x 10 mM (in DMSO)$275In Stock
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Purity:99.71%
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Product Introduction

Bioactivity
Description
(1S,4R)-N-DesmethylSertralineHydrochloride is a Serotonin transporter and Norepinephrine transporter inhibitor with IC50 of 19 nM and 35 nM, respectively.
Chemical Properties
Molecular Weight328.66
FormulaC16H16Cl3N
Cas No.675126-07-5
Smiles[H]Cl.N[C@@H]1CC[C@@H](C2=CC=C(Cl)C(Cl)=C2)C3=C1C=CC=C3
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 60 mg/mL (182.56 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.0427 mL15.2133 mL30.4266 mL152.1329 mL
5 mM0.6085 mL3.0427 mL6.0853 mL30.4266 mL
10 mM0.3043 mL1.5213 mL3.0427 mL15.2133 mL
20 mM0.1521 mL0.7607 mL1.5213 mL7.6066 mL
50 mM0.0609 mL0.3043 mL0.6085 mL3.0427 mL
100 mM0.0304 mL0.1521 mL0.3043 mL1.5213 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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